Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 Biomarker disease BEFREE These results infer functional differences between two homologous enzymes and indicate that quinone reductase 2 could play important roles in the regulation of catecholamine oxidation processes that may be involved in the etiology of Parkinson disease. 18579530 2008
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 GeneticVariation disease LHGDN The results suggest that the association of the D promoter with Parkinson's disease may be due to an increase in expression of the NQO2 gene. 18314446 2008
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 AlteredExpression disease BEFREE The results suggest that the association of the D promoter with Parkinson's disease may be due to an increase in expression of the NQO2 gene. 18314446 2008
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 Biomarker disease LHGDN These results infer functional differences between two homologous enzymes and indicate that quinone reductase 2 could play important roles in the regulation of catecholamine oxidation processes that may be involved in the etiology of Parkinson disease. 18579530 2008
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 GeneticVariation disease BEFREE We investigated associations of genetic polymorphisms of NQO1 (C609T) and NQO2 (I/D, 29 base pairs) with PD in a population-based case-control study of 190 idiopathic PD cases and 305 unrelated controls matched on age and sex. 15694256 2005
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 GeneticVariation disease LHGDN These studies also suggest that alterations in NQO2 activity might be an important factor in susceptibility to Parkinson's disease. 15451063 2004
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 GeneticVariation disease BEFREE These studies also suggest that alterations in NQO2 activity might be an important factor in susceptibility to Parkinson's disease. 15451063 2004
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 GeneticVariation disease LHGDN We conducted a study of the potential association between idiopathic Parkinson's disease and polymorphisms of GSTM1, NQO1, and NQO2. 11688992 2001