NOS1, nitric oxide synthase 1, 4842

N. diseases: 521; N. variants: 38
Disease: Pyloric Stenosis, Hypertrophic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease BEFREE Genomic variants in the coding region of neuronal nitric oxide synthase (NOS1) in infantile hypertrophic pyloric stenosis. 22008325 2011
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 GeneticVariation disease BEFREE No association between a promoter NOS1 polymorphism (rs41279104) and Infantile Hypertrophic Pyloric Stenosis. 19851341 2009
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease MGD Impairment of endothelial nitric oxide synthase causes abnormal fat and glycogen deposition in liver. 18206129 2008
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease MGD Neuronal nitric oxide synthase controls enzyme activity pattern of mitochondria and lipid metabolism. 16246868 2006
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease MGD Combined loss of neuronal and endothelial nitric oxide synthase causes premature mortality and age-related hypertrophic cardiac remodeling in mice. 12788381 2003
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease MGD Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms. 11907582 2002
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease MGD Differences in peripheral nerve degeneration/regeneration between wild-type and neuronal nitric oxide synthase knockout mice. 11992469 2002
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease MGD Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes. 12081996 2002
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease MGD Altered respiratory responses to hypoxia in mutant mice deficient in neuronal nitric oxide synthase. 9679181 1998
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease MGD Impaired ovulation in mice with targeted deletion of the neuronal isoform of nitric oxide synthase. 9848082 1998
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease MGD The role of nitric oxide and NMDA receptors in the development of motor neuron dendrites. 9852587 1998
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 AlteredExpression disease BEFREE We examined the expression of the neuronal NOS gene at the messenger RNA (mRNA) level in pyloric smooth-muscle biopsy specimens from six patients with infantile hypertrophic pyloric stenosis (IHPS) using a reverse transcription-polymerase chain reaction (RT-PCR) technique. 9354728 1997
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 GeneticVariation disease BEFREE Genetic evidence for the neuronal nitric oxide synthase gene (NOS1) as a susceptibility locus for infantile pyloric stenosis. 8571963 1996
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease MGD Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase. 7477374 1995
CUI: C0700639
Disease: Pyloric Stenosis, Hypertrophic
Pyloric Stenosis, Hypertrophic 		0.240 Biomarker disease MGD Targeted disruption of the neuronal nitric oxide synthase gene. 7505721 1993