|
Malignant neoplasm of breast
|
0.600 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
|
Malaria
|
0.400 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
Essential Hypertension
|
0.330 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
Diabetes Mellitus, Insulin-Dependent
|
0.250 |
Biomarker
|
disease |
MGD |
|
|
|
|
Elevated systolic blood pressure
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Elevated diastolic blood pressure
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Elevated mean arterial pressure
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Serous cystadenocarcinoma ovary
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A cis-diamminedichloroplatinum (II) (CDDP)-resistant cell line (NOS2CR) demonstrated 7.4-fold greater resistance to CDDP compared with the parental cell line (NOS2) established from a patient with serous cystadenocarcinoma of the ovary.
|
7909418 |
1994 |
|
Human immunodeficiency virus (HIV) II infection category B1
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
These results demonstrate that HIV-1 can influence the expression of NOS in both cultured human monocytes and brain tissue.
|
7530762 |
1995 |
|
Brain Diseases
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Corresponding iNOS mRNA was not detected in brain tissue from five AIDS patients who died with less significant brain disease.
|
7530762 |
1995 |
|
Schizophrenia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Schizophreniform disorder, DD and PD-NOS constituted 6.4%, 2.8% and 7.5%, respectively, of all probands with a registry diagnosis of schizophrenia.
|
7676834 |
1995 |
|
HIV Encephalopathy
|
0.010 |
Biomarker
|
disease |
BEFREE |
In support of this hypothesis, RNA encoding the inducible NO synthase (iNOS) was detected in postmortem brain tissue from one pediatric AIDS patient with advanced HIV encephalitis.
|
7530762 |
1995 |
|
pediatric AIDS
|
0.010 |
Biomarker
|
disease |
BEFREE |
In support of this hypothesis, RNA encoding the inducible NO synthase (iNOS) was detected in postmortem brain tissue from one pediatric AIDS patient with advanced HIV encephalitis.
|
7530762 |
1995 |
|
HIV encephalitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
In support of this hypothesis, RNA encoding the inducible NO synthase (iNOS) was detected in postmortem brain tissue from one pediatric AIDS patient with advanced HIV encephalitis.
|
7530762 |
1995 |
|
Colitis
|
0.530 |
Biomarker
|
disease |
CTD_human |
Colitis and interleukin 1beta up-regulate inducible nitric oxide synthase and superoxide dismutase in rat myenteric neurons.
|
8698225 |
1996 |
|
Toxic Shock Syndrome
|
0.500 |
Biomarker
|
disease |
CTD_human |
Expression of inducible nitric oxide synthase in failing and non-failing human heart.
|
8745224 |
1996 |
|
Psoriasis
|
0.440 |
AlteredExpression
|
disease |
BEFREE |
Messenger RNA for the iNOS enzyme (iNOS mRNA) was detected by reverse transcriptase polymerase chain reaction in skin biopsies from patients with psoriasis, but not in skin specimens from patients with atopic eczema or from healthy volunteers.
|
8920887 |
1996 |
|
Congestive heart failure
|
0.360 |
Biomarker
|
disease |
BEFREE |
Western blot analysis with the same primary antibody showed a specific positive band for iNOS protein in the heart failure specimens; minimal iNOS protein expression was seen in donor heart samples.
|
8653828 |
1996 |
|
Heart failure
|
0.350 |
Biomarker
|
disease |
BEFREE |
Western blot analysis with the same primary antibody showed a specific positive band for iNOS protein in the heart failure specimens; minimal iNOS protein expression was seen in donor heart samples.
|
8653828 |
1996 |
|
Endotoxic shock
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Expression of inducible nitric oxide synthase in failing and non-failing human heart.
|
8745224 |
1996 |
|
Septic Shock
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Expression of inducible nitric oxide synthase in failing and non-failing human heart.
|
8745224 |
1996 |
|
Lung diseases
|
0.210 |
Biomarker
|
group |
RGD |
Expression of inducible nitric oxide synthase and its involvement in pulmonary granulomatous inflammation in rats.
|
8952535 |
1996 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Biopsied renal tissues from patients with IgA nephropathy (IgAN; 28 cases) and with non-IgA mesangial proliferative glomerulonephritis (PGN;12 cases), and normal renal tissues obtained from kidneys removed for malignancies (11 cases) were included in this experiment. iNOS message was present in about 73% tissues from IgAN and PGN patients, which was supported by histochemical findings and the iNOS positive cells were predominantly in the tubulointerstitial areas where infiltration of monocytes/macrophages was abundant.
|
8840265 |
1996 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
However, in contrast to reports by others, we could demonstrate that tumor cells and not MO are the producers of NO by the following findings: 1) NO release was induced in RT4 cells, but not in MO, by diluted supernatants (SN) of RT4/MO cocultures; 2) SN of MO stimulated with tumor cell membrane preparations were sufficient to induce NO release by tumor cells; and 3) NOS mRNA expression could be detected only in tumor cells, not in MO.
|
8757334 |
1996 |
|
Adenocarcinoma
|
0.080 |
GeneticVariation
|
group |
BEFREE |
Tissue specimens of normal salivary glands (n = 23), pleomorphic adenomas (n = 60), basal cell adenomas (n = 6), canalicular ademomas (n = 2), myoepitheliomas (n = 2), adenoid cystic carcinomas (n = 26) and adenocarcinomas NOS (n = 11) were evaluated for the expression of S-100A1, S-100A2, A-100A4, S-100A6 and S-100B by using highly specific polyclonal and monoclonal antibodies generated against the recombinant human protein.
|
8986967 |
1996 |