|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The single nucleotide polymorphisms (SNPs) of eNOS were found to be associated with many kidney diseases.
|
28946141 |
2017 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphism (SNP) genotype has been associated with a worse phenotype amongst patients with established heart failure and in patients with progression of their renal disease.
|
25612295 |
2015 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Several eNOS gene polymorphisms have been reported as 'susceptibility genes' in various human diseases states, including cardiovascular, pulmonary and renal diseases.
|
25699607 |
2015 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Evidence indicates the contribution of 4a allele of endothelial NO synthase (eNOS) gene to cardiac and renal diseases.
|
25263931 |
2015 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Polymorphisms of eNOS gene may be involved in the progression of renal disease, and may be the causative factors that contribute to the deterioration of renal functions.
|
24673298 |
2014 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
NOS3 894G>T polymorphism is associated with progression of kidney disease and cardiovascular morbidity in type 2 diabetic patients: NOS3 as a modifier gene for diabetic nephropathy?
|
24603156 |
2013 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
In obese subjects, NOS3 4a (P=0.011) had a converse effect to NOS3 894T (P=0.043), and EDN1 8002T (P=0.035) on the prevalence of combined microangiopathy (neuropathy/retinopathy/nephropathy) vs. microangiopathy-negative subjects.
|
21406182 |
2011 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
No associations between the -786T>C, the VNTR intron 4 a/b and the 894G>T (Glu298Asp) polymorphisms in the eNOS gene and renal disease were observed in type 2 diabetic Caucasian-Brazilians.
|
21255858 |
2011 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
A polymorphism in intron 4 of the endothelial constitutive nitric oxide synthase (ecNOS) gene is a candidate gene in cardiovascular and renal diseases.
|
21519233 |
2011 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Our study indicated an association between the risk of lupus nephropathy and the sequence variations of both the ACE gene and the eNOS gene, which may play an important role in the pathogenesis of lupus nephropathy in the northern Chinese population.
|
20540812 |
2010 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
We found no association of the eNOS polymorphism with the development of renal disease.
|
19965945 |
2010 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The A allele of rs1800783 is a significant risk factor for nephropathy in individuals with type 1 diabetes, and further comprehensive studies are warranted to confirm the definitive functional variant in the NOS3 gene.
|
20962522 |
2010 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Candidate-gene association studies that examined the association between polymorphisms of endothelial nitric oxide synthase (NOS3) gene (G894T, 4b/a, and T786C) and diabetic nephropathy or diabetes leading to severe nephropathy produced inconclusive results.
|
19773668 |
2009 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The G894T polymorphism of the eNOS gene is associated with severity of renal disease.
|
19376104 |
2009 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Associations between seven NOS3-gene polymorphisms and nephropathy, progression of nephropathy and CVD were studied.
|
19246226 |
2009 |
|
Kidney Diseases
|
0.100 |
Biomarker
|
group |
LHGDN |
Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation.
|
18256374 |
2008 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
In the endothelial nitric oxide synthase (eNOS) intron 4 polymorphism, the presence of the aa genotype has been associated with cardiovascular and renal disease.
|
17498125 |
2007 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The role of endothelial nitric oxide synthase gene intron 4 a/b (eNOS4a/b) variable number of tandem repeats (VNTR) polymorphism in various renal diseases was investigated.
|
16941147 |
2006 |
|
Kidney Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
We hypothesized that polymorphisms in the genes coding for ACE and eNOS may influence the development and/or progression of systemic lupus erythematosus (SLE) and lupus nephritis given their linkage with other renal diseases.
|
15338496 |
2004 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Patients with eNOS(GT) genotype showed more rapid deterioration in renal function, higher incidence of overt nephropathy and lower renal survival than those with eNOS(GG) genotype.
|
15331206 |
2004 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
A polymorphism in intron 4 of the ecNOS gene is a candidate gene in cardiovascular and renal diseases.
|
15299097 |
2004 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Association of ecNOS gene polymorphisms with end stage renal diseases.
|
12701818 |
2003 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Polymorphism in intron 4 of the ecNOS gene is implicated in cardiovascular and renal diseases.
|
14580231 |
2003 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
We investigated the relationship between endothelial NO synthase (eNOS) gene polymorphism, apolipoprotein E (apoE) polymorphism, and carotid atherosclerosis in 163 hemodialysis patients with nondiabetic nephropathy.
|
12666069 |
2003 |
|
Kidney Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
We examined polymorphisms within NOS3 and NOS2A, the genes encoding endothelial- and inducible nitric oxide synthase, for association with nephropathy.
|
12687343 |
2003 |