NOS3, nitric oxide synthase 3, 4846

N. diseases: 706; N. variants: 39
Disease: Neointimal hyperplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.030 AlteredExpression disease BEFREE Excess vessel wall thickening in mice lacking NOS3 was partially reversed by simultaneous deletion of MMP-13, indicating that NOS3 prevents neointimal hyperplasia by preventing MMP-13 activity. 24925976 2014
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.030 Biomarker disease BEFREE Both eNOS-EPCs transplantation (p<0.05) and GFP-EPCs transplantation (p<0.05) could inhibit neointimal hyperplasia compared with saline injection. 20888843 2011
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.030 Biomarker disease BEFREE In this study, we examined the hypothesis that overexpression of vasculoprotective gene endothelial nitric oxide synthase (eNOS) and heme oxygenase-1 (HO-1) in EPCs enhances their ability to inhibit neointimal hyperplasia. 15066951 2004