NOTCH1, notch receptor 1, 4851

N. diseases: 693; N. variants: 64
Disease: Acute periodontitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001342
Disease: Acute periodontitis
Acute periodontitis 		0.010 AlteredExpression disease BEFREE The down-regulation of Notch 1 and Jagged 1 and loss of their osteoprotective function might cause a more excessive osteoclast formation and contribute to greater osteolysis in aggressive periodontitis. 31468527 2019