NOTCH1, notch receptor 1, 4851

N. diseases: 693; N. variants: 64
Disease: Anoxia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003130
Disease: Anoxia
Anoxia 		0.020 Biomarker phenotype LHGDN Taken together, these findings demonstrate that Notch1 is a key effector of both Akt and hypoxia in melanoma development and identify the Notch signaling pathway as a potential therapeutic target in melanoma treatment. 18924608 2008
CUI: C0003130
Disease: Anoxia
Anoxia 		0.020 Biomarker phenotype LHGDN Notch signaling mediates hypoxia-induced tumor cell migration and invasion. 18427106 2008