NOTCH1, notch receptor 1, 4851

N. diseases: 693; N. variants: 64
Disease: Skin Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0037286
Disease: Skin Neoplasms
Skin Neoplasms 		0.310 Biomarker group CTD_human Whole-Exome Sequencing Validates a Preclinical Mouse Model for the Prevention and Treatment of Cutaneous Squamous Cell Carcinoma. 27923803 2017
CUI: C0037286
Disease: Skin Neoplasms
Skin Neoplasms 		0.310 AlteredExpression group BEFREE Epidermal cell differentiation and skin tumor suppression were caused by a p53-dependent transcriptional activation of the metalloprotease TACE/ADAM17 (TNF-α-converting enzyme), a previously unknown p53 target gene that was required for NOTCH1 activation. 22772468 2012