NOTCH2, notch receptor 2, 4853

N. diseases: 384; N. variants: 30
Disease: Stomach Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.050 AlteredExpression disease BEFREE Both Notch1 and Notch2 mRNA expressions were elevated in GC tissues and peripheral bloods in GC patients. 30988066 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.050 AlteredExpression disease BEFREE ACGs inhibited GC cells' viability in a dose dependent manner and led to cell apoptosis and cell cycle arrest in G0/G1 phase with an increased Notch2 expression. 28416750 2017
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.050 AlteredExpression disease BEFREE Notch2-induced COX-2 expression enhancing gastric cancer progression. 21976141 2012
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.050 Biomarker disease BEFREE Notch2 may negatively regulate cell invasion by inhibiting the PI3K-Akt signaling pathway in gastric cancer. 23326131 2012
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.050 Biomarker disease BEFREE The results of the differential expression analysis indicate a prominent role for NOTCH2 and chemotherapy resistance in GC, which seems to be related to an effect of the drugs on NOTCH2 expression rather than to an enrichment of NOTCH2 expressing tumour cells. 22970250 2012