NOTCH2, notch receptor 2, 4853

N. diseases: 384; N. variants: 30
Disease: B-CELL MALIGNANCY, LOW-GRADE ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.040 AlteredExpression disease BEFREE We investigated the in vitro ability of four such oligomers to reduce the expression of Notch2 gene in peripheral blood mononuclear cells from B-CLL patients. 22161246 2012
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.040 AlteredExpression disease BEFREE These data indicate that downregulation of CD23 and loss of Notch2 activity are early steps in PI-induced apoptosis of B-CLL lymphocytes and may be part of the full apoptotic response. 15565166 2005
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.040 AlteredExpression disease BEFREE Regulation of CD23 expression by Notch2 in B-cell chronic lymphocytic leukemia. 15621797 2005
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.040 AlteredExpression disease BEFREE Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia. 11986231 2002