NOTCH3, notch receptor 3, 4854

N. diseases: 418; N. variants: 71
Disease: Arteriovascular degeneration ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0264954
Disease: Arteriovascular degeneration
Arteriovascular degeneration 		0.010 Biomarker disease BEFREE This molecular genetic signature of CADASIL has led to the hypothesis that structural abnormalities in the vascular smooth-muscle protein NOTCH3 trigger arterial degeneration, vascular protein accumulation, and cerebrovascular failure. 29478611 2018