NPM1, nucleophosmin 1, 4869

N. diseases: 283; N. variants: 7
Disease: Glioblastoma Multiforme ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.040 Biomarker disease BEFREE The present review article is focused on two important markers in current research viz.Prominin-1 and NPM1 in glioblastoma. 28770964 2017
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.040 AlteredExpression disease BEFREE NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape. 26559910 2015
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.040 Biomarker disease BEFREE In conclusion, NPM proved to participate in the apoptotic process, sensitizing TMZ-treated U87MG and A172 cells to cell death, and in association with upregulation of GRP78 may be helpful as a predictive factor of poor prognosis in GBM patients. 22745010 2012
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.040 AlteredExpression disease BEFREE Semi-quantitative RT-PCR experiments with 6 of those genes confirmed higher expression of DNCH2, ARHGEF6, NPM1 and SRI and lower expression of NRGN and TM4SF2 in GBM tumors. 16320026 2006