NPPA, natriuretic peptide A, 4878

N. diseases: 217; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085580
Disease: Essential Hypertension
Essential Hypertension
0.030 GeneticVariation disease BEFREE Studies evaluating the association between the atrial natriuretic peptide (ANP) genetic polymorphism and the risk of essential hypertension (EH) have reported inconsistent results. 27136577 2016
CUI: C0085580
Disease: Essential Hypertension
Essential Hypertension
0.030 Biomarker disease BEFREE Our results suggest that the down-regulation of ANP gene expression at mRNA and protein levels and up-regulated CYP11B2 protein expression levels may be correlated with the essential hypertension and could serve as circulating prognostic biomarkers for essential hypertension. 25917967 2015
CUI: C0085580
Disease: Essential Hypertension
Essential Hypertension
0.030 GeneticVariation disease BEFREE Neither G1837A nor the T2238C polymorphism of the ANP gene was associated with EH. 11409652 2001