Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.030 AlteredExpression group BEFREE Our findings indicate that targeting the Ei24-ATP2a2 interaction to increase ATP2a2 activity can protect pancreatic β cells and improve glucose homeostasis in diabetic models, suggesting that Ei24 could potentially serve as a target to prevent or manage diabetes. 29769309 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.030 AlteredExpression group BEFREE However, the role of SERCA2 down-regulation in the pathophysiology of diabetes mellitus and diabetic cardiomyopathy is not yet well described. 25270119 2014
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.030 AlteredExpression group BEFREE Therefore, SERCA2 expression might constitute an important therapeutic target to rescue cardiac SR Ca2+ handling in diabetes. 12206992 2002