Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis
0.030 AlteredExpression disease BEFREE This complication in sepsis is linked to reduced levels in cardiomyocytes of three critical proteins (SERCA2, NCX, Na<sup>+</sup> /K<sup>+</sup> -ATPase). 30821872 2019
CUI: C0243026
Disease: Sepsis
Sepsis
0.030 AlteredExpression disease BEFREE The present study aimed to investigate the effects of acute sepsis on diaphragm contractility and relaxation, via examining the Ca2+‑uptake function of sarco/endoplasmic reticulum Ca2+ adenosine triphosphatase (SERCA), and the protein levels of SERCA1, SERCA2 and the ryanodine receptor (RyR) of the sarcoplasmic reticulum (SR). 28765908 2017
CUI: C0243026
Disease: Sepsis
Sepsis
0.030 Biomarker disease BEFREE In the absence of C5a receptors, defects in SERCA2 and NCX in CMs after sepsis are strikingly attenuated. 27931779 2017