NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Disease: Follicular adenoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0205647
Disease: Follicular adenoma
Follicular adenoma 		0.030 GeneticVariation disease BEFREE Total mutations found in the FNA and in the corresponding histological specimen in both series were: one PAX8/PPARG rearrangement in a follicular carcinoma (FC), four NRAS mutations [in two FCs, one papillary carcinoma and one follicular adenoma (FA)] and one HRAS mutation in one FA. 25487739 2015
CUI: C0205647
Disease: Follicular adenoma
Follicular adenoma 		0.030 GeneticVariation disease BEFREE Activating H-, K-, or N-Ras mutations are commonly detected in follicular adenomas and carcinomas of the thyroid gland. 10334566 1999
CUI: C0205647
Disease: Follicular adenoma
Follicular adenoma 		0.030 GeneticVariation disease BEFREE A similar genetic abnormality of N-ras genes at codon 61 between follicular adenoma and follicular carcinoma suggests that the mutation of N-ras at codon 61 might play a part in oncogenesis in follicular tumors. 7704243 1995