NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Disease: Follicular Variant Thyroid Gland Papillary Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3714651
Disease: Follicular Variant Thyroid Gland Papillary Carcinoma
Follicular Variant Thyroid Gland Papillary Carcinoma 		0.040 GeneticVariation disease BEFREE Nonetheless, NRAS mutation was also found in I-EFVPTC. 31671409 2019
CUI: C3714651
Disease: Follicular Variant Thyroid Gland Papillary Carcinoma
Follicular Variant Thyroid Gland Papillary Carcinoma 		0.040 GeneticVariation disease BEFREE In contrast, NRAS, HRAS and KRAS mutations were observed more often in encapsulated FVPTCs (48.6% in non-invasive and 66.7% in invasive) than in infiltrative FVPTCs (15.4%) (P < 0.001). 28940583 2018
CUI: C3714651
Disease: Follicular Variant Thyroid Gland Papillary Carcinoma
Follicular Variant Thyroid Gland Papillary Carcinoma 		0.040 GeneticVariation disease BEFREE Overall, 13 cases (46%) harbored RAS mutations, including seven (25%) with NRAS mutations (p.Gln61Arg) and six (21%) with HRAS mutations (five had p.Gln61Arg and one had a p.Gln61Lys substitution).No PE/WC FVPTCs had BRAF mutations. 23477374 2013
CUI: C3714651
Disease: Follicular Variant Thyroid Gland Papillary Carcinoma
Follicular Variant Thyroid Gland Papillary Carcinoma 		0.040 GeneticVariation disease BEFREE RET-PTC and PAX8-PPARgamma rearrangements and mutations of the neuroblastoma RAS viral oncogene homolog N-RAS at codon 61 were the most common genetic alterations in FVPTCs. 20564403 2010