NTF3, neurotrophin 3, 4908

N. diseases: 38; N. variants: 1
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.300 Biomarker disease CTD_human Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine. 8635431 1996
CUI: C0270823
Disease: Petit mal status
Petit mal status 		0.300 Biomarker disease CTD_human Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine. 8635431 1996
CUI: C0311335
Disease: Grand Mal Status Epilepticus
Grand Mal Status Epilepticus 		0.300 Biomarker disease CTD_human Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine. 8635431 1996
CUI: C0393734
Disease: Complex Partial Status Epilepticus
Complex Partial Status Epilepticus 		0.300 Biomarker disease CTD_human Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine. 8635431 1996
CUI: C0751522
Disease: Status Epilepticus, Subclinical
Status Epilepticus, Subclinical 		0.300 Biomarker disease CTD_human Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine. 8635431 1996
CUI: C0751523
Disease: Non-Convulsive Status Epilepticus
Non-Convulsive Status Epilepticus 		0.300 Biomarker disease CTD_human Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine. 8635431 1996
CUI: C0751524
Disease: Simple Partial Status Epilepticus
Simple Partial Status Epilepticus 		0.300 Biomarker phenotype CTD_human Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine. 8635431 1996
CUI: C0011882
Disease: Diabetic Neuropathies
Diabetic Neuropathies 		0.310 Therapeutic group CTD_human Continuous delivery of neurotrophin 3 by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies. 11779407 2001
CUI: C0271673
Disease: Symmetric Diabetic Proximal Motor Neuropathy
Symmetric Diabetic Proximal Motor Neuropathy 		0.300 Therapeutic disease CTD_human Continuous delivery of neurotrophin 3 by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies. 11779407 2001
CUI: C0271674
Disease: Asymmetric Diabetic Proximal Motor Neuropathy
Asymmetric Diabetic Proximal Motor Neuropathy 		0.300 Therapeutic disease CTD_human Continuous delivery of neurotrophin 3 by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies. 11779407 2001
CUI: C0271678
Disease: Diabetic Mononeuropathy
Diabetic Mononeuropathy 		0.300 Therapeutic disease CTD_human Continuous delivery of neurotrophin 3 by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies. 11779407 2001
CUI: C0271680
Disease: Diabetic Polyneuropathies
Diabetic Polyneuropathies 		0.300 Therapeutic group CTD_human Continuous delivery of neurotrophin 3 by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies. 11779407 2001
CUI: C0271685
Disease: Diabetic Amyotrophy
Diabetic Amyotrophy 		0.300 Therapeutic disease CTD_human Continuous delivery of neurotrophin 3 by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies. 11779407 2001
CUI: C0271686
Disease: Diabetic Autonomic Neuropathy
Diabetic Autonomic Neuropathy 		0.300 Therapeutic disease CTD_human Continuous delivery of neurotrophin 3 by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies. 11779407 2001
CUI: C0393835
Disease: Diabetic Asymmetric Polyneuropathy
Diabetic Asymmetric Polyneuropathy 		0.300 Therapeutic disease CTD_human Continuous delivery of neurotrophin 3 by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies. 11779407 2001
CUI: C0751074
Disease: Diabetic Neuralgia
Diabetic Neuralgia 		0.300 Therapeutic disease CTD_human Continuous delivery of neurotrophin 3 by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies. 11779407 2001
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Therapeutic phenotype CTD_human Continuous infusion is required for suppression of both thermal hyperalgesia and TRPV1 expression, because removal of NT-3 resulted in a prompt reestablishment of the hyperalgesic state and corresponding CCI-associated TRPV1 phenotype. 15659614 2005
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.300 Therapeutic phenotype CTD_human Differential damage to auditory neurons and hair cells by ototoxins and neuroprotection by specific neurotrophins in rat cochlear organotypic cultures. 8921280 1996
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.300 Therapeutic phenotype CTD_human Neurotrophin protection against toxicity induced by low potassium and nitroprusside in cultured cerebellar granule neurons. 8978711 1997
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.310 Therapeutic phenotype CTD_human Neurotrophin-3 suppresses thermal hyperalgesia associated with neuropathic pain and attenuates transient receptor potential vanilloid receptor-1 expression in adult sensory neurons. 15659614 2005
CUI: C2936719
Disease: Mechanical Allodynia
Mechanical Allodynia 		0.310 Therapeutic phenotype CTD_human Neurotrophin-3 suppresses thermal hyperalgesia associated with neuropathic pain and attenuates transient receptor potential vanilloid receptor-1 expression in adult sensory neurons. 15659614 2005
CUI: C0458247
Disease: Allodynia
Allodynia 		0.300 Therapeutic phenotype CTD_human Neurotrophin-3 suppresses thermal hyperalgesia associated with neuropathic pain and attenuates transient receptor potential vanilloid receptor-1 expression in adult sensory neurons. 15659614 2005
CUI: C0751211
Disease: Hyperalgesia, Primary
Hyperalgesia, Primary 		0.300 Therapeutic phenotype CTD_human Neurotrophin-3 suppresses thermal hyperalgesia associated with neuropathic pain and attenuates transient receptor potential vanilloid receptor-1 expression in adult sensory neurons. 15659614 2005
CUI: C0751212
Disease: Hyperalgesia, Secondary
Hyperalgesia, Secondary 		0.300 Therapeutic phenotype CTD_human Neurotrophin-3 suppresses thermal hyperalgesia associated with neuropathic pain and attenuates transient receptor potential vanilloid receptor-1 expression in adult sensory neurons. 15659614 2005
CUI: C0751213
Disease: Tactile Allodynia
Tactile Allodynia 		0.300 Therapeutic phenotype CTD_human Neurotrophin-3 suppresses thermal hyperalgesia associated with neuropathic pain and attenuates transient receptor potential vanilloid receptor-1 expression in adult sensory neurons. 15659614 2005