Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0155305
Disease: Optic Neuropathy, Ischemic
Optic Neuropathy, Ischemic
0.010 Biomarker disease BEFREE TrkB receptor partial agonist LM22A-4 promoted survival of cultured RGCs in vitro by TrkB receptor activation, and treatment in vivo led to increased survival of RGCs after optic nerve ischemia, providing support that LM22A-4 may be effective therapy to treat ischemic optic neuropathy. 30273053 2018