NTS, neurotensin, 4922

N. diseases: 184; N. variants: 1
Disease: Small cell carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.040 Biomarker disease BEFREE Vasoactive intestinal peptide (VIP) increases the secretion rate of BB-like peptide and NTS from SCLC leading to increased proliferation. 30008698 2018
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.040 Biomarker disease BEFREE Antagonists have been developed for GRP, NT and AM receptors which function as cytostatic agents and inhibit SCLC growth. 16633328 2006
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.040 AlteredExpression disease BEFREE A hallmark of small cell lung carcinoma (SCLC) is the expression of autocrine growth factors such as neurotensin and gastrin-releasing peptide, which bind to cellular receptors and stimulate cell division. 10915224 2000
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.040 Biomarker disease BEFREE Although the biomarkers L-Dopa decarboxylase, bombesin, carcinoembryonic antigen, and neurotensin were detectable in SCLC-22H, they were undetectable or low in SCLC-21H. 3028617 1987