OAS2, 2'-5'-oligoadenylate synthetase 2, 4939

N. diseases: 38; N. variants: 4
Disease: Psoriasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.020 AlteredExpression disease BEFREE Despite differences in the specific residues targeted for methylation/demethylation, OAS2 expression was upregulated in all conditions and correlations between methylation and expression were seen in psoriasis and tongue SCC. 27572959 2016
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.020 Biomarker disease BEFREE Increased expression of four antiviral proteins (MX1, BST2, ISG15 and OAS2) has been reported in psoriatic skin and genetic studies of psoriasis have identified susceptibility genes in antiviral pathways. 25809693 2015