OAS3, 2'-5'-oligoadenylate synthetase 3, 4940

N. diseases: 72; N. variants: 15
Disease: Zika Virus Infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0276289
Disease: Zika Virus Infection
Zika Virus Infection 		0.010 AlteredExpression disease BEFREE Finally, when synthetic double-stranded RNA was detected by OAS3 to induce RNase L antiviral activity prior to ZIKV infection, we observed reduced ZIKV replication factory formation, as well as a 42-fold reduction in virus yield in WT but not RNase L KO cells. 31142667 2019