|
Mood Disorders
|
0.300 |
Biomarker
|
group |
PSYGENET |
Overall, each gene was associated with at least one main outcome: anxiety (SAT1, SMS), mood disorders (SAT1, SMOX), and suicide attempts (SAT1, OATL1).
|
21152090 |
2010 |
|
Neoplasms
|
0.020 |
GeneticVariation
|
group |
BEFREE |
One monophasic epithelial and two monophasic fibrous synovial sarcomas showed an OATL2-associated breakpoint, while a biphasic tumour revealed a hybridization pattern indicating a breakpoint within the OATL1 region.
|
7790992 |
1995 |
|
Wiskott-Aldrich Syndrome
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
This cosmid contains the gene responsible for Wiskott-Aldrich syndrome (WAS) and localizes the disease gene between OATL1 and GATA.
|
8530079 |
1995 |
|
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
We speculate that there seems to be a relationship between the occurrence of these breakpoint regions and the histologic phenotype of the tumors, with a predominance of OATL1-related breakpoints in the classical biphasic tumors and of OATL2-related breakpoints in the monophasic fibrous tumors.
|
8174096 |
1994 |
|
Wiskott-Aldrich Syndrome
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
These linkage data narrow the boundaries within which the WAS locus maps to the chromosomal region bracketed by TIMP and DXS146 and support the loci order Xpter-DXS7-TIMP-(OATL1, WAS, DXS255)-DXS146.
|
1346773 |
1992 |
|
Anxiety Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Externalizing behaviors demonstrated significant mediation with regards to the association between OATL1 and attempted suicide, however there was no evidence that externalizing or internalizing behaviors were appropriate endophenotypes to explain the associations with mood or anxiety disorders.
|
21152090 |
2010 |
|
Alveolar Soft Part Sarcoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
To define the interval containing the Xp11.2 break, we first performed FISH on ASPS cases using YAC probes for OATL1 (Xp11.23) and OATL2 (Xp11.21), and cosmid probes from the intervening genomic region.
|
11244503 |
2001 |
|
synovial sarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
A yeast artificial chromosome (YAC) clone (OAT YAC2) which hybridizes to a human OAT cDNA probe and is known to contain part of the OATL1 cluster was selected and used to confirm these results both by fluorescence in situ hybridization on synovial sarcoma patient material and by hybridization of its end-clones to the der(X) containing hybrid cells.
|
7682104 |
1993 |
|
Adult Synovial Sarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
A yeast artificial chromosome (YAC) clone (OAT YAC2) which hybridizes to a human OAT cDNA probe and is known to contain part of the OATL1 cluster was selected and used to confirm these results both by fluorescence in situ hybridization on synovial sarcoma patient material and by hybridization of its end-clones to the der(X) containing hybrid cells.
|
7682104 |
1993 |
|
Childhood Synovial Sarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
A yeast artificial chromosome (YAC) clone (OAT YAC2) which hybridizes to a human OAT cDNA probe and is known to contain part of the OATL1 cluster was selected and used to confirm these results both by fluorescence in situ hybridization on synovial sarcoma patient material and by hybridization of its end-clones to the der(X) containing hybrid cells.
|
7682104 |
1993 |
|
Mental Retardation, X-Linked 9
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In this study, we performed linkage analysis of MRX9 with a panel of 43 polymorphic DNA markers dispersed over chromosome X. Two-point linkage analysis revealed lod scores of 3.52 and 3.82 at 0% recombination for OATL1 and MAOA, both located in Xp11.2-p11.4.
|
8288232 |
1993 |
|
Papillary Renal Cell Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Our results indicate that the two translocation breakpoints differ from each other and that the chromosomal break in t(X;1)-positive papillary renal cell carcinoma is located between the markers PFC-TIMP-OATL1-SYP-TFE3 and DXS226-DXS146-DXS255-OATL2-DXS14.
|
8406438 |
1993 |