|
Xeroderma Pigmentosum, Complementation Group D
|
0.090 |
Biomarker
|
disease |
BEFREE |
Our findings support XRCC1, XRCC3, hOGG1, and XPD as risk genes for schizophrenia and suggest that altered DNA repair functions may be involved in schizophrenia pathophysiology.
|
26554302 |
2016 |
|
Xeroderma Pigmentosum, Complementation Group D
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Genotyping of XPD Asp³¹²Asn was performed by amplification refractory mutation system PCR assay and genotyping of OGG1 Ser³²⁶Cys was carried out by PCR including confronting two-pair primers.
|
24868140 |
2014 |
|
Xeroderma Pigmentosum, Complementation Group D
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Seven studies (1,955 HCC cases and 2,023 controls) for XPD Lys751Gln polymorphism and six studies (1,470 HCC cases and 1,541 controls) for hOGG1 Ser326Cys polymorphism were included in the final meta-analysis.
|
23271362 |
2013 |
|
Xeroderma Pigmentosum, Complementation Group D
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
To analyze the association of the polymorphisms in 8-oxoguanine glycosylase-1 (OGG1), X-ray repair cross-complementing-1 (XRCC1), and AP endonuclease-1 (APE1) genes in the base excision repair pathway and xeroderma pigmentosum complementation group D (XPD) in the nucleotide excision repair pathway with the risk of cataract in a Chinese population.
|
22306120 |
2012 |
|
Xeroderma Pigmentosum, Complementation Group D
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
The percent difference of mean relative expression between cases and controls demonstrated maximum lowering in OGG1 (47.3%) > XPD (30.7%) > XRCC1 (25.2%).
|
22081374 |
2012 |
|
Xeroderma Pigmentosum, Complementation Group D
|
0.090 |
Biomarker
|
disease |
BEFREE |
A significant joint effect of cigarette smoking, alcohol consumption and both hOGG1 and XPD risk genotypes increases UC risk and UC cases carrying both hOGG1 and XPD risk genotypes have a significantly greater risk of high grade tumor.
|
22110223 |
2011 |
|
Xeroderma Pigmentosum, Complementation Group D
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
The XPD and the hOGG1 genes are highly polymorphic, and some of their polymorphisms are associated with several types of cancers.
|
19561388 |
2009 |
|
Xeroderma Pigmentosum, Complementation Group D
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
In a population-based case-control study, we examined associations of the hOGG1 Ser 326 Cys, XRCC1 Arg 399 Gln, and XPD Lys 751 Gln polymorphisms with risk of esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
|
18349297 |
2008 |
|
Xeroderma Pigmentosum, Complementation Group D
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G>A), ERCC2/XPD (Lys751Gln) and ERCC5/XPD (His46His); the BER genes APE1/APEX (Ile64Val), OGG1 (Ser326Cys), PCNA (1876A>G) and XRCC1 (Arg194Trp, Arg280His, Arg399Gln); and the DSB-R genes ATR (Thr211Met), NBS1 (Glu185Gln), XRCC2 (Arg188His) and XRCC9 (Thr297Ile) modulate NSCLC risk.
|
16195237 |
2006 |