OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Disease: Alcoholic Intoxication ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001969
Disease: Alcoholic Intoxication
Alcoholic Intoxication 		0.300 Biomarker disease PSYGENET Different trajectories of adolescent alcohol use: testing gene-environment interactions. 24134200 2014
CUI: C0001969
Disease: Alcoholic Intoxication
Alcoholic Intoxication 		0.300 Biomarker disease PSYGENET Subjective response to alcohol among alcohol-dependent individuals: effects of the μ-opioid receptor (OPRM1) gene and alcoholism severity. 23240711 2013
CUI: C0001969
Disease: Alcoholic Intoxication
Alcoholic Intoxication 		0.300 Biomarker disease PSYGENET Stress-induced and cue-induced craving for alcohol in heavy drinkers: Preliminary evidence of genetic moderation by the OPRM1 and CRH-BP genes. 21039637 2011
CUI: C0001969
Disease: Alcoholic Intoxication
Alcoholic Intoxication 		0.300 Biomarker disease PSYGENET Naltrexone selectively elevates GABAergic neuroactive steroid levels in heavy drinkers with the Asp40 allele of the OPRM1 gene: a pilot investigation. 20528823 2010
CUI: C0001969
Disease: Alcoholic Intoxication
Alcoholic Intoxication 		0.300 Biomarker disease PSYGENET Endorsing the expectation of a more intense response on one or more of the following items from the SHAS-E: buzzed, clumsy, dizzy, drunk, effects, high, nausea, sleepy, talkative, terrible, and/or uncomfortable after imbibing 2-3 drinks was significantly associated with having at least one minor allele for at least one of 7 SNPs (p < 0.01) in the OPRM1 receptor gene. 18433502 2008