OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Disease: Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003864
Disease: Arthritis
Arthritis 		0.020 Biomarker disease BEFREE A bivalent compound targeting CCR5 and the mu opioid receptor treats inflammatory arthritis pain in mice without inducing pharmacologic tolerance. 30053832 2018
CUI: C0003864
Disease: Arthritis
Arthritis 		0.020 AlteredExpression disease BEFREE Our results indicate that prophylactic therapy with MOR overexpression in joints can successfully prevent the development of pain, dysfunction, and histopathologic abnormalities in the joints in arthritis. 17530644 2007