OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Disease: Fibromyalgia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0016053
Disease: Fibromyalgia
Fibromyalgia 		0.040 GeneticVariation disease BEFREE We also confirmed that the rs1799971 SNP (opioid receptor μ1 gene) might confer genetic risk of fibromyalgia. 29486785 2018
CUI: C0016053
Disease: Fibromyalgia
Fibromyalgia 		0.040 GeneticVariation disease BEFREE We hypothesized that the OPRM1 polymorphism may play a role in fibromyalgia susceptibility and impact the pain intensity and pain-related symptoms in fibromyalgia patients. 24671502 2014
CUI: C0016053
Disease: Fibromyalgia
Fibromyalgia 		0.040 Biomarker disease BEFREE The purpose of the present investigation was to determine if variation in the catechol-O-methyltransferase (COMT) and mu-opioid receptor (OPRM1) genes is associated with pain-related positive affective regulation in fibromyalgia (FM). 20230086 2010
CUI: C0016053
Disease: Fibromyalgia
Fibromyalgia 		0.040 Biomarker disease LHGDN MOR BP in the accumbens of FM patients was negatively correlated with affective pain ratings. 17855614 2007