PRDX1, peroxiredoxin 1, 5052

N. diseases: 237; N. variants: 3
Disease: Anoxia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003130
Disease: Anoxia
Anoxia 		0.020 AlteredExpression phenotype LHGDN Although the cell survival-enhancing property of Prx1 has traditionally been attributed to its antioxidant activity, the reactive oxygen species-scavenging activity of Prx1 was not essential for AR stimulation because Prx1 itself was oxidized and inactivated by hypoxia/reoxygenation. 17909037 2007
CUI: C0003130
Disease: Anoxia
Anoxia 		0.020 AlteredExpression phenotype LHGDN Preferential elevation of Prx I and Trx expression in lung cancer cells following hypoxia and in human lung cancer tissues. 14703116 2003