PAH, phenylalanine hydroxylase, 5053

N. diseases: 219; N. variants: 394
Disease: Cardiovascular Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.020 GeneticVariation group BEFREE Our data suggest that exposure of coke oven workers to PAH can lead to increased systemic acute response and therefore potentially increased risk of cardiovascular disease. 31477116 2019
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.020 AlteredExpression group BEFREE Our data show that reported enhanced ACE2 activity in cardiovascular disease should not significantly compromise the beneficial effects of apelin based therapies for example in PAH. 28293165 2017