SERPINE1, serpin family E member 1, 5054

N. diseases: 770; N. variants: 23
Disease: Scleroderma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011644
Disease: Scleroderma
Scleroderma 		0.010 AlteredExpression disease BEFREE TGF-beta signaling events, including phosphorylation of Smad2 and -3, and transcription of the PAI-1 gene are increased in scleroderma fibroblasts, relative to normal fibroblasts. 11904440 2002