SERPINE1, serpin family E member 1, 5054

N. diseases: 770; N. variants: 23
Disease: Premature aging syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0231341
Disease: Premature aging syndrome
Premature aging syndrome 		0.010 Biomarker disease BEFREE Plasminogen activator inhibitor-1 (PAI-1), a major inhibitor of fibrinolysis, is associated with thrombosis, obesity, insulin resistance, dyslipidemia, and premature aging, which all are coexisting conditions of chronic obstructive pulmonary disease (COPD). 28356730 2017