SERPINE1, serpin family E member 1, 5054

N. diseases: 770; N. variants: 23
Disease: Coinfection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0275524
Disease: Coinfection
Coinfection 		0.010 Biomarker phenotype BEFREE In the development cohort, increased levels of a serum module containing IL6, IL8, IL10, IP10, GCSF, MCP1, and MIP1α [shock odds ratio (OR) = 3.37, family-wise error rate (FWER) <i>p</i> < 10<sup>-4</sup>], and decreased levels of a module containing EGF, FGF2, SCD40L, and PAI-1 (shock OR = 0.43, FWER <i>p</i> = 0.002), were both associated with ALI, shock, and death-ECMO independent of age and bacterial coinfection. 29163498 2017