SERPINE1, serpin family E member 1, 5054
N. diseases: 770; N. variants: 23
Source: ALL
| Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year |
|---|---|---|---|---|---|---|---|
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0.040 | Biomarker | disease | BEFREE | <i>Helicobacter pylori colonizes</i> the stomach in about half of the world's population.<i>H. pylori</i> strains containing the <i>cag</i> pathogenicity island (<i>cag</i> PAI) are associated with a higher risk of gastric adenocarcinoma or peptic ulcer disease compared to <i>cag</i> PAI-negative strains. | 31712269 | 2020 |
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0.040 | AlteredExpression | disease | BEFREE | We determined the distribution of Helicobacter pylori outer membrane protein Q (HopQ) allelic type, cytotoxin-associated gene (cag)-pathogenicity activity island (cag-PAI) and vacuolation activating cytotoxin A (vacA) genes, respectively, in patients with B-cell NHL. | 29143724 | 2017 |
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0.040 | GeneticVariation | disease | BEFREE | Several genes including the cagA in the cag pathogenicity island (cag PAI) of Helicobacter pylori are thought to be associated with the gastroduodenal diseases and hence variation in the genetic structure of the cag PAI might be responsible for different clinical outcomes. | 21195664 | 2011 |
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0.040 | Biomarker | disease | BEFREE | Expressions of urokinase-type plasminogen activator, its receptor and plasminogen activator inhibitor-1 in gastric cancer cells and effects of Helicobacter pylori. | 16109653 | 2005 |