IL22, interleukin 22, 50616

N. diseases: 551; N. variants: 9
Disease: polyps ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032584
Disease: polyps
polyps 		0.040 Biomarker phenotype BEFREE In patients without polyps (CRSsNP), IL-21 correlated positively with Extranasal Rhinologic Symptoms domain (R<sub>s</sub> = 0.41, p = 0.01). 30629853 2019
CUI: C0032584
Disease: polyps
polyps 		0.040 Biomarker phenotype BEFREE Flow cytometry revealed that the source of IL-21 was predominantly CD4+ T cells and that IL-21+CD4+ T cells were significantly increased in polyp tissue and further increased after SEB stimulation. 29131072 2017
CUI: C0032584
Disease: polyps
polyps 		0.040 AlteredExpression phenotype BEFREE In the previous study, we found that the levels of IL-21 in nasal polyps (NPs) were significantly increased and associated with polyp size and recurrence. 26239551 2015
CUI: C0032584
Disease: polyps
polyps 		0.040 AlteredExpression phenotype BEFREE Polyp IL-21 level was significantly associated with polyp size, tissue eosinophilia and asthma comorbidity, and recurrence after surgery (P < 0.05). 25495679 2015