REG3A, regenerating family member 3 alpha, 5068

N. diseases: 148; N. variants: 1
Disease: Colitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009319
Disease: Colitis
Colitis 		0.030 AlteredExpression disease BEFREE PAP-1 also reduced the expression of Kv1.3, iNOS, NLRP3, caspase-1p20 and IL-1β on macrophages in colitis mice. 31351364 2019
CUI: C0009319
Disease: Colitis
Colitis 		0.030 Biomarker disease BEFREE PAP protein plays a protective effect presenting anti-inflammatory properties able to reduce the severity of colitis, preserving gut barrier and epithelial inflammation. 31325218 2019
CUI: C0009319
Disease: Colitis
Colitis 		0.030 Biomarker disease BEFREE Fecal microbiota from REG3A-TG mice protect non-TG mice from induction of colitis. 29133078 2018