PRKN, parkin RBR E3 ubiquitin protein ligase, 5071

N. diseases: 409; N. variants: 88
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019163
Disease: Hepatitis B
Hepatitis B
0.040 AlteredExpression disease BEFREE Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation. 30733490 2019
CUI: C0019163
Disease: Hepatitis B
Hepatitis B
0.040 Biomarker disease BEFREE Hepatitis B virus X protein activates E3 ubiquitin ligase Siah-1 to control virus propagation via a negative feedback loop. 28714848 2017
CUI: C0019163
Disease: Hepatitis B
Hepatitis B
0.040 Biomarker disease BEFREE We observed that the HBx oncoprotein of hepatitis B virus regulates E2F1 functions by interfering with its binding to Skp2 E3 ubiquitin ligase. 23868976 2013
CUI: C0019163
Disease: Hepatitis B
Hepatitis B
0.040 Biomarker disease BEFREE E3 ubiquitin ligase Siah-1 facilitates poly-ubiquitylation and proteasomal degradation of the hepatitis B viral X protein. 21878328 2011