PAX3, paired box 3, 5077

N. diseases: 257; N. variants: 62
Disease: Malignant neoplasm of stomach ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.040 AlteredExpression disease BEFREE At 10q23.33, the rs3781266[C] and rs3740365[T] risk alleles in complete linkage disequilibrium disrupted and created, respectively, the binding motifs of POU2F1 and PAX3, resulting in an increased enhancer activity and expression of <i>NOC3L</i>, while the <i>NOC3L</i> knockdown suppressed GC cell growth. 31383772 2020
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.040 Biomarker disease BEFREE The aim of the study is to investigate the effects and mechanism of PAX3 silencing on the gastric cancer. 31847528 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.040 AlteredExpression disease BEFREE MiR-658, paired box gene 3 (PAX3) and met proto-oncogene (MET) are overexpressed in gastric cancer while PAX3 and MET can be regulated by miRNA. 29630524 2018
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.040 AlteredExpression disease BEFREE In addition, PAX3 expression was markedly higher in GC tissues than in adjacent non-cancerous tissues. 25653235 2015