PAX3, paired box 3, 5077

N. diseases: 257; N. variants: 62
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 AlteredExpression disease BEFREE At 10q23.33, the rs3781266[C] and rs3740365[T] risk alleles in complete linkage disequilibrium disrupted and created, respectively, the binding motifs of POU2F1 and PAX3, resulting in an increased enhancer activity and expression of <i>NOC3L</i>, while the <i>NOC3L</i> knockdown suppressed GC cell growth. 31383772 2020
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 Biomarker disease BEFREE The aim of the study is to investigate the effects and mechanism of PAX3 silencing on the gastric cancer. 31847528 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 AlteredExpression disease BEFREE MiR-658, paired box gene 3 (PAX3) and met proto-oncogene (MET) are overexpressed in gastric cancer while PAX3 and MET can be regulated by miRNA. 29630524 2018
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 AlteredExpression disease BEFREE In addition, PAX3 expression was markedly higher in GC tissues than in adjacent non-cancerous tissues. 25653235 2015