PAX7, paired box 7, 5081

N. diseases: 78; N. variants: 8
Disease: Sarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1261473
Disease: Sarcoma
Sarcoma 		0.040 AlteredExpression group BEFREE One EWSR1-NFATC2 sarcoma co-expressed PAX7 and NKX2-2. 29920735 2018
CUI: C1261473
Disease: Sarcoma
Sarcoma 		0.040 Biomarker group BEFREE Global gene expression profiling revealed particularly prominent differential expression of genes, including ITGA7, MYF5, MYF6, MYOD1, MYOG, and PAX7, involved in muscle development and function, providing strong argument for grouping inflammatory leiomyosarcoma with myogenic sarcomas, rather than with myofibroblastic lesions. 28884746 2018
CUI: C1261473
Disease: Sarcoma
Sarcoma 		0.040 AlteredExpression group BEFREE No PAX7 expression was observed in any of 27 cases of CIC-DUX4 sarcoma by immunohistochemistry (0%; 0/27). 28643791 2017
CUI: C1261473
Disease: Sarcoma
Sarcoma 		0.040 Biomarker group BEFREE Furthermore, mechanistic studies revealed that Pax7 can promote sarcoma metastasis in vivo through MyoD-dependent regulation of pro-metastatic miR-182. 26234681 2016