FOXP3, forkhead box P3, 50943

N. diseases: 688; N. variants: 27
Disease: Infantile Colic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0266836
Disease: Infantile Colic
Infantile Colic 		0.020 Biomarker phenotype BEFREE Crying Time and RORγ/FOXP3 Expression in Lactobacillus reuteri DSM17938-Treated Infants with Colic: A Randomized Trial. 28969887 2018
CUI: C0266836
Disease: Infantile Colic
Infantile Colic 		0.020 AlteredExpression phenotype BEFREE Our findings showed increased mRNA expression of the transcription factor forkhead box P3 (FoxP3) in infants treated with <i>L. reuteri</i> DSM 17938 for 28 days (<i>P</i><0.009) and increased TLR2 and TLR4 mRNA expression in both treated and placebo subjects.After <i>L. reuteri</i> administration for 28 days in infants with colic, we observed a significant decrease in daily crying time (302.3±19.86 min/day on day 0 vs 76.75±22.15 min/day on day 28, <i>P</i>=0.001). 30406696 2018