|
Autism Spectrum Disorders
|
0.310 |
Biomarker
|
disease |
CTD_human |
Notwithstanding complexities, our results further implicate the SHANK3-NLGN4-NRXN1 postsynaptic density genes and also identify novel loci at DPP6-DPP10-PCDH9 (synapse complex), ANKRD11, DPYD, PTCHD1, 15q24, among others, for a role in ASD susceptibility.
|
18252227 |
2008 |
|
Autism Spectrum Disorders
|
0.310 |
Biomarker
|
disease |
BEFREE |
Notwithstanding complexities, our results further implicate the SHANK3-NLGN4-NRXN1 postsynaptic density genes and also identify novel loci at DPP6-DPP10-PCDH9 (synapse complex), ANKRD11, DPYD, PTCHD1, 15q24, among others, for a role in ASD susceptibility.
|
18252227 |
2008 |
|
Liver carcinoma
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Genome-Wide Association Study Identifies a Genetic Prediction Model for Postoperative Survival in Patients with Hepatocellular Carcinoma.
|
30945699 |
2019 |
|
Liver carcinoma
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Genomewide association study for C-reactive protein in Indians replicates known associations of common variants.
|
30945673 |
2019 |
|
Liver carcinoma
|
0.130 |
Biomarker
|
disease |
BEFREE |
Salivary lnc-PCDH9-13:1 is a desirable biomarker for early HCC.
|
30045829 |
2018 |
|
Liver carcinoma
|
0.130 |
PosttranslationalModification
|
disease |
BEFREE |
Methylation of the PCDH9 promoter was observed in 22% primary HCC tissues (24/111 tumors).
|
28791409 |
2017 |
|
Liver carcinoma
|
0.130 |
AlteredExpression
|
disease |
BEFREE |
We identified PCDH9 as a novel regulator of EMT by increasing the activity of GSK-3β and inhibiting Snail1, indicating its potential therapeutic value for reducing metastasis of HCC.
|
25172662 |
2014 |
|
Major Depressive Disorder
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
|
30718901 |
2019 |
|
Major Depressive Disorder
|
0.110 |
Biomarker
|
disease |
BEFREE |
These convergent lines of evidence suggest that PCDH9 is likely a novel risk gene for MDD.
|
28990594 |
2018 |
|
Major Depressive Disorder
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Common variants on 6q16.2, 12q24.31 and 16p13.3 are associated with major depressive disorder.
|
29728651 |
2018 |
|
Major Depressive Disorder
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.
|
29942085 |
2018 |
|
Major Depressive Disorder
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Identification of 15 genetic loci associated with risk of major depression in individuals of European descent.
|
27479909 |
2016 |
|
Child Development Disorders, Pervasive
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
Identification of common genetic risk variants for autism spectrum disorder.
|
30804558 |
2019 |
|
Smoking
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
|
30643258 |
2019 |
|
Potassium measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits.
|
31409800 |
2019 |
|
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
|
30239722 |
2019 |
|
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Chronic Obstructive Airway Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
The genetics of smoking in individuals with chronic obstructive pulmonary disease.
|
29631575 |
2018 |
|
Adolescent idiopathic scoliosis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
|
30019117 |
2018 |
|
mathematical ability
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
|
30038396 |
2018 |
|
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
|
30019117 |
2018 |
|
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association study on obesity and obesity-related traits.
|
21552555 |
2011 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study on obesity and obesity-related traits.
|
21552555 |
2011 |
|
Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
We identified five putative clustered deleted tumor suppressor genes and provided experimental and clinical evidence that PCDH9, deleted/loss in approximately 23% of tumors, functions as a novel tumor suppressor gene with prognostic potential in PCa.
|
28927585 |
2018 |