PCK1, phosphoenolpyruvate carboxykinase 1, 5105

N. diseases: 73; N. variants: 12
Disease: Leprosy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023343
Disease: Leprosy
Leprosy 		0.010 Biomarker disease BEFREE Our analysis highlights the anaplerotic enzyme phosphoenolpyruvate carboxylase required for this intracellular diet of <i>M. leprae</i>, identifying this enzyme as a potential antileprosy drug target.<b>IMPORTANCE</b> Leprosy remains a major problem in the world today, particularly affecting the poorest and most disadvantaged sections of society in the least developed countries of the world. 31848273 2019