ANGPTL4, angiopoietin like 4, 51129

N. diseases: 21; N. variants: 5
Disease: Obesity ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.400 Therapeutic disease CTD_human We show here that the purified FLD of Angptl4 is sufficient to stimulate lipolysis in mouse primary adipocytes and that increasing circulating FLD levels in mice through adenovirus-mediated overexpression (Ad-FLD) not only induces WAT lipolysis <i>in vivo</i> but also reduces diet-induced obesity without affecting LPL activity. 28842503 2017