INSIG2, insulin induced gene 2, 51141

N. diseases: 45; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias
0.020 GeneticVariation group BEFREE To identify polymorphisms in INSIG2 which are associated with overweight (BMI ≥ 85% for age) and dyslipidemia in children. 25607990 2015
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias
0.020 GeneticVariation group BEFREE One particularly interesting single nucleotide polymorphism (SNP), rs7566605, located 10 kb upstream of INSIG2 was reported to have the strongest association with obesity among 86 604 SNP, while the relationship with dyslipidaemia is uncertain. 18570692 2009