ING4, inhibitor of growth family member 4, 51147

N. diseases: 92; N. variants: 2
Disease: Dysplastic Nevus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0205748
Disease: Dysplastic Nevus
Dysplastic Nevus 		0.010 Biomarker disease BEFREE Using the tissue microarray technology, we found that ING4 expression is significantly decreased in malignant melanoma compared with dysplastic nevi (P < 0.0001, chi(2) test) and reduced ING4 staining is associated with melanoma thickness, ulceration (P = 0.034 and 0.002, respectively, chi(2) test) as well as poor overall and disease-specific 5-year survival of primary melanoma patients (P = 0.0002 and 0.001, respectively, chi(2) test). 18375955 2008