DCTN4, dynactin subunit 4, 51164

N. diseases: 253; N. variants: 4
Disease: Arteriosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.040 Biomarker disease BEFREE Finally, the recent literature focusing on p62 and selective autophagy in metabolism and the spectrum of cardiometabolic diseases including atherosclerosis, fatty liver disease, and obesity is evaluated. 30588824 2019
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.040 Biomarker disease BEFREE Our study offers a rationale for the development of autophagy and p62 as a new target for the treatment of atherosclerosis. 31101336 2019
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.040 Biomarker disease BEFREE Little is known about the role and significance of p62 accumulation in atherosclerosis. 29285070 2017
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.040 Biomarker disease BEFREE Aortas from atherosclerotic mice and plaques from human endarterectomy samples showed increased abundance of p62 and polyubiquitinated proteins that colocalized with plaque macrophages, suggesting that p62-enriched protein aggregates were characteristic of atherosclerosis. 26732762 2016