GP6, glycoprotein VI platelet, 51206

N. diseases: 89; N. variants: 11
Disease: Platelet thrombus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0333209
Disease: Platelet thrombus
Platelet thrombus 		0.020 Biomarker disease BEFREE This is important for the understanding of plaque-triggered platelet thrombus formation and is clinically relevant for future GPVI-targeting therapies with recombinant GPVI-Fc and anti-GPVI antibodies. 29378359 2018
CUI: C0333209
Disease: Platelet thrombus
Platelet thrombus 		0.020 Biomarker disease BEFREE GPVI-CD39 effectively stimulated local ADP degradation and, compared with GPVI-Fc alone, led to significantly increased inhibition of ADP-, collagen-, and human plaque-induced platelet aggregation in Multiplate aggregometry and plaque-induced platelet thrombus formation under arterial flow conditions. 28751543 2017