TLR7, toll like receptor 7, 51284

N. diseases: 276; N. variants: 13
Disease: Myocardial rupture ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018813
Disease: Myocardial rupture
Myocardial rupture 		0.010 Biomarker disease BEFREE Compared to wild type mice, TLR7-/- mice had less acute cardiac rupture associated with blunted activation of matrix metalloproteinase 2, increased expression of tissue inhibitor of metalloproteinase 1, recruitment of more myofibroblasts, and the formation of a myocardial scar with higher collagen fibre density. 30830156 2019