TLR8, toll like receptor 8, 51311

N. diseases: 122; N. variants: 8
Disease: Crohn Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.030 GeneticVariation disease BEFREE Association of haplotypes of the TLR8 locus with susceptibility to Crohn's and Behçet's diseases. 26486764 2016
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.030 AlteredExpression disease BEFREE TLR-8 mRNA and protein expression were substantially up-regulated in CEC from inflamed mucosa from patients with ulcerative colitis (approximately 350-fold, p<0.01) and Crohn's disease (approximately 45-fold, p<0.05) compared to controls. 18985539 2009
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.030 GeneticVariation disease BEFREE Both "risk (H4)" and "protective (H1)" TLR8 haplotypes were observed associated with CD in females. 18942751 2009