Disease: Solid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.040 Biomarker phenotype BEFREE Phase I Study of Enavatuzumab, a First-in-Class Humanized Monoclonal Antibody Targeting the TWEAK Receptor, in Patients with Advanced Solid Tumors. 29054986 2018
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.040 Biomarker phenotype BEFREE Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors. 26446946 2016
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.040 AlteredExpression phenotype BEFREE These results indicate that oncogenic Src may contribute to Fn14 overexpression in solid tumors, and that Src-mediated cell invasion could potentially be inhibited with Fn14-targeted therapeutics. 25392346 2015
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.040 Biomarker phenotype BEFREE Antitumor activity of a humanized, bivalent immunotoxin targeting fn14-positive solid tumors. 23722548 2013